Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Synthetic peptide: C-KTEISFRPNDPKSYE (with a Cysteine residue linker), corresponding to internal sequence amino acids 85-99 of Human beta Sodium Potassium ATPase (NP_001668.1; NP_001001787.1).
Applications
Application Notes
WB: 0.1 - 0.3μg/ml; IHC-P: 5μg/ml;
Target
Alternative Names
ATP1B1; ATPase, Na+/K+ transporting, beta 1 polypeptide; ATP1B; sodium/potassium-transporting ATPase subunit beta-1; adenosinetriphosphatase; sodium pump subunit beta-1; Na, K-ATPase beta-1 polypeptide; Beta 1-subunit of Na(+),K(+)-ATPase; sodium/potassiu
Product Background
Antigen Description
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.
Pathway
Adrenergic signaling in cardiomyocytes; Aldosterone-regulated sodium reabsorption; Basigin interactions; Bile secretion
Citations
Publication ()
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COA
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