Anti-ATG12 monoclonal antibody (DCABH-220) Knockout Validated

Rabbit anti-Human ATG12 monoclonal antibody for ICC, WB, IHC-P

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Clone
FQS5911
Species Reactivity
Human
Immunogen
Synthetic peptide corresponding to residues on the C-terminus in Human Apg12.
Conjugate
Unconjugated

Applications


Application Notes
ICC: 1/250 - 1/500; WB: 1/1000 - 1/10000; IHC-P: 1/250 - 1/500.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
ATG12; ATG12 autophagy related 12 homolog (S. cerevisiae); Apg12 (autophagy 12, S. cerevisiae) like , APG12 autophagy 12 like (S. cerevisiae) , APG12L; ubiquitin-like protein ATG12; APG12; APG12 autophagy 12 like
Entrez Gene ID
UniProt ID

Product Background


Pathway
Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; Negative regulators of RIG-I/MDA5 signaling, organism-specific biosystem; RIG-I-like receptor signaling pathway, organism-specific biosystem; RIG-I-like receptor signaling pathway, conserved biosystem; RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways, organism-specific biosystem; Regulation of autophagy, organism-specific biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Saitoh, T; Fujita, N; et al. Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1 beta production. NATURE 456:264-U68(2008).
Le, XF; Mao, WQ; et al. Dasatinib Induces Autophagic Cell Death in Human Ovarian Cancer. CANCER 116:4980-4990(2010).

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