Synthetic peptide corresponding to a region within C terminal amino acids 358-407 (SVVIFSGEGS DELTQGYIYF HKAPSPEKAE EESERLLREL YLFDVLRADR) of Human Asparagine synthetase (NP_001664).
The protein encoded by this gene is involved in the synthesis of asparagine. This gene complements a mutation in the temperature-sensitive hamster mutant ts11, which blocks progression through the G1 phase of the cell cycle at nonpermissive temperature. Alternatively spliced transcript variants have been described for this gene.
Pathway
ATF4 activates genes; Alanine, aspartate and glutamate metabolism; Metabolism; Metabolism of proteins
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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He, YY; Li, BS; et al. Asparagine Synthetase Is Partially Localized to the Plasma Membrane and Upregulated by L-asparaginase in U937 Cells. JOURNAL OF HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY-MEDICAL SCIENCES 31:159-163(2011).
Richards, NGJ; Kilberg, MS; et al. Asparagine synthetase chemotherapy. ANNUAL REVIEW OF BIOCHEMISTRY 75:629-654(2006).
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