Specifications
Immunogen
Recombinant fragment, corresponding to amino acids 71-171 of Human ASMT (NP_004034), with proprietary tag. Mol Wt 37.498 kDa.
Applications
Application Notes
Sandwich ELISA: 10 μg/ml.
Target
Alternative Names
ASMT; acetylserotonin O-methyltransferase; ASMTY; HIOMT; HIOMTY; hydroxyindole O-methyltransferase; acetylserotonin N-methyltransferase; acetylserotonin methyltransferase (Y chromosome);
Product Background
Antigen Description
This gene belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland. Alternatively spliced transcript variants have been noted for this gene.
Pathway
Amine-derived hormones, organism-specific biosystem; Biogenic Amine Synthesis, organism-specific biosystem; Melatonin biosynthesis, tryptophan => serotonin => melatonin, organism-specific biosystem; Melatonin biosynthesis, tryptophan => serotonin =>
Citations
Publication ()
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COA
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