The protein encoded by this gene is a member of the sulfatase family. Sulfatases are essential for the correct composition of bone and cartilage matrix. The encoded protein is postranslationally glycosylated and localized to the lysosome. This gene is located within a cluster of similar arylsulfatase genes on chromosome X. A related pseudogene has been identified in the pseudoautosomal region of chromosome Y.
Pathway
Estrogen metabolism; Glycosphingolipid metabolism; Metabolism; Metabolism of lipids and lipoproteins; Metabolism of proteins; PTM: gamma carboxylation, hypusine formation and arylsulfatase activation; Post-translational protein modification; Sphingolipid metabolism; The activation of arylsulfatases.
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