A region within Synthetic peptide: LSGYLERDIS QDSLQDIKQK VQDKYRYCES RRRVLLQHVH EGYEKDLWEY, corresponding to C terminal amino acids 505-554 of Human ARIH1
Might act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2L3/UBCM4, and then transfers it to substrates.
Pathway
Antiviral mechanism by IFN-stimulated genes; Cytokine Signaling in Immune system; ISG15 antiviral mechanism; Immune System; Interferon Signaling;
Citations
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