Anti-ARID4A (aa 1033-1139) polyclonal antibody

Species Reactivity

Human

Immunogen

ARID4A (NP_002883, 1033 a.a. ~ 1139 a.a) partial recombinant protein with GST tag. The sequence is AEESQEGLCERESANGFETNVASGTCSIIVQERESREKGQKRPSDGNSGLMAKKQKRTPK RTSAAAKNEKNGTGQSSDSEDLPVLDNSSKCTPVKHLNVSKPQKLAR

Conjugate

Alternative Names

ARID4A; AT rich interactive domain 4A (RBP1-like); RBP1; RBBP1; RBP-1; RBBP-1; AT-rich interactive domain-containing protein 4A; retinoblastoma binding protein 1; retinoblastoma-binding protein 1; ARID domain-containing protein 4A;

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein. This protein, in turn, serves as a bridging molecule to recruit HDACs and, in addition, provides a second HDAC-independent repression function. The encoded protein possesses transcriptional repression activity. Multiple alternatively spliced transcripts have been observed for this gene, although not all transcript variants have been fully described.