Recombinant GST fusion protein corresponding to 209 mouse Arhgef2. The sequence is SRANSRDGEAGRAAVASVTPEKQATELALLQRQHTLLQEELRRCQRLGEERATEAGSLEA RLRESEQARALLEREAEEIRRQLAALGQNEPLPAEAPWARRPLDPRRRSLPAGDALYLSF NPPQPSRGHDRLDLPVTVRSLHRPFDDREAQELGSPEDRLQDSSDPDTGSEEEVSSRLSP PHSPRDFTRMQDIPEETESRDGEPTASES
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:1000. & The optimal working dilution should be determined by the end user.
ARHGEF2 (Rho/Rac guanine nucleotide exchange factor (GEF) 2) is a protein-coding gene. Diseases associated with ARHGEF2 include paralysis, and motor neuron disease, and among its related super-pathways are Development Slit-Robo signaling and NRAGE signals death through JNK. GO annotations related to this gene include microtubule binding and phospholipid binding. An important paralog of this gene is ARHGEF12.
Pathway
Cell death signalling via NRAGE, NRIF and NADE; GPCR downstream signaling; Rho GTPase cycle; Signaling by GPCR
Citations
Publication ()
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