ARHGAP6 (NP_038286, 531 a.a. ~ 636 a.a) partial recombinant protein with GST tag. The sequence is RHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEESTAIIAV VQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSS
Conjugate
Unconjugated
Target
Alternative Names
ARHGAP6; Rho GTPase activating protein 6; RHOGAP6; RHOGAPX-1; rho GTPase-activating protein 6; rho-type GTPase-activating protein 6; Rho-type GTPase-activating protein RhoGAPX-1;
This gene encodes a member of the rhoGAP family of proteins which play a role in the regulation of actin polymerization at the plasma membrane during several cellular processes. This protein is thought to have two independent functions, one as a GTPase-activating protein with specificity for RhoA, and another as a cytoskeletal protein that promotes actin remodeling. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Pathway
Regulation of RhoA activity; Signal Transduction.
Citations
Publication ()
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