Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 62-93 of Human CENTD1 (NP_056045.2)
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/100 - 1/500.
Target
Alternative Names
ARAP2; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2; PARX; CENTD1; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2; cnt-d1; centaurin-delta-1; centaurin, delta 1; Arf and Rho GAP adapter protein 2;
The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. This protein lacks the predicted catalytic arginine in the RHO-GAP domain and is therefore unlikely to have RHO-GAP activity. While the encoded protein does contain a sterile alpha motif (SAM) commonly found in some signaling molecules, the function of the protein has not been determined. Two transcript variants encoding different isoforms have been found for this gene.
Pathway
Arf6 signaling events; Endocytosis; Rap1 signaling pathway; Signal Transduction.
Citations
Publication ()
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COA
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