Anti-AQP4 monoclonal antibody (DCABH-10320)

Specifications


Host Species
Mouse
Antibody Isotype
IgG3
Clone
5/29
Species Reactivity
Mouse, Rat, Rabbit, Human, Zebrafish
Immunogen
Synthetic peptide: VIDIDRGDEKKGKDSSGE, corresponding to amino acids 301-318 of Aquaporin 4
Conjugate
Unconjugated

Applications


Application Notes
IHC-P: 1/100.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
AQP4; aquaporin 4; aquaporin-4; WCH4; aquaporin 4.M23; mercurial-insensitive water channel
Entrez Gene ID
UniProt ID

Product Background


Pathway
Aquaporin-mediated transport, organism-specific biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Regulation of Water Balance by Renal Aquaporins, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem; Vasopressin-regulated water reabsorption, organism-specific biosystem; Vasopressin-regulated water reabsorption, conserved biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Kim, SM; Waters, P; et al. Utility of aquaporin-4 antibody assay in patients with neuromyelitis optica spectrum disorders. MULTIPLE SCLEROSIS JOURNAL 19:1060-1067(2013).
Takahashi, T; Fujihara, K; et al. Anti-aquaporin-4 antibody is involved in the pathogenesis of NMO: a study on antibody titre. BRAIN 130:1235-1243(2007).

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