Anti-APOBEC3F (aa 274-372) polyclonal antibody

Species Reactivity

Human

Immunogen

APOBEC3F (NP_660341, 274 a.a. ~ 372 a.a) partial recombinant protein with GST tag. The sequence is YTSWSPCPECAGEVAEFLARHSNVNLTIFTARLYYFWDTDYQEGLRSLSQEGASVEIMGY KDFKYCWENFVYNDDEPFKPWKGLKYNFLFLDSKLQEIL

Conjugate

Alternative Names

APOBEC3F; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F; A3F; KA6; ARP8; BK150C2.4.MRNA; DNA dC->dU-editing enzyme APOBEC-3F; induced upon T-cell activation; apolipoprotein B mRNA editing enzyme cytidine deaminase; apolipoprotein

Entrez Gene ID

UniProt ID

Antigen Description

This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been identified.

Pathway

APOBEC3G mediated resistance to HIV-1 infection; HIV Infection; Vif-mediated degradation of APOBEC3G;