Anti-APH1B monoclonal antibody (DCABH-10546) Made to order

Rabbit anti-Human APH1B monoclonal antibody for WB, ELISA

View other APH1B antibodies

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
A synthetic peptide of human APH1B is used for rabbit immunization.
Conjugate
Unconjugated

Target


Alternative Names
APH1B; anterior pharynx defective 1 homolog B (C. elegans); gamma-secretase subunit APH-1B; APH 1B; DKFZp564D0372; PSFL
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activated NOTCH1 Transmits Signal to the Nucleus, organism-specific biosystem; Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; NRIF signals cell death from the nucleus, organism-specific biosystem; Notch signaling pathway, organism-specific biosystem; Nuclear signaling by ERBB4, organism-specific biosystem; Presenilin action in Notch and Wnt signaling, organism-specific biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Serneels, L; Dejaegere, T; et al. Differential contribution of the three Aph1 genes to gamma-secretase activity in vivoi. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102:1719-1724(2005).
Marlow, L; Canet, RM; et al. APH1, PEN2, and Nicastrin increase A beta levels and gamma-secretase activity. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 305:502-509(2003).

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