AP4E1 (NP_031373, 1038 a.a. ~ 1137 a.a) partial recombinant protein with GST tag. The sequence is SDDFGKLWLSFANDVKQNVKMSESQAALPSALKTLQQKLRLHIIEIIGNEGLLACQLLPS IPCLLHCRVHADVLALWFRSSCSTLPDYLLYQCQKVMEGS
Conjugate
Unconjugated
Target
Alternative Names
AP4E1; adaptor-related protein complex 4, epsilon 1 subunit; CPSQ4; SPG51; AP-4 complex subunit epsilon-1; epsilon-adaptin; adaptor-related protein complex AP-4 epsilon;
This gene encodes a member of the adaptor complexes large subunit protein family. These proteins are components of the heterotetrameric adaptor protein complexes, which play important roles in the secretory and endocytic pathways by mediating vesicle formation and sorting of integral membrane proteins. The encoded protein is a large subunit of adaptor protein complex-4, which is associated with both clathrin- and nonclathrin-coated vesicles. Disruption of this gene may be associated with cerebral palsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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