Anti-TFAP2A monoclonal antibody, clone B7/3/3

Name: Anti-TFAP2A monoclonal antibody, clone B7/3/3
SKU: DCABH-9290
Rating: 5 (1 reviews)

Mouse anti-Human TFAP2A monoclonal antibody for SDS-PAGE, FC, WB, ELISA, IHC-P, RIA, ICC/IF

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COA

SDS

Datasheet

Summary

Specifications

Antibody Isotype

IgG1

Clone

B7/3/3

Species Reactivity

Human

Immunogen

C-terminal peptide of AP-2 alpha (PNSHTDNNAKSSDKEEKHRK).

Conjugate

Unconjugated

Applications

Application Notes

SDS-PAGE: 1/1500; ICC/IF: 1 μg/ml.

Target

Alternative Names

TFAP2A; transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha); AP2TF, TFAP2, transcription factor AP 2 alpha (activating enhancer binding protein 2 alpha); transcription factor AP-2-alpha; AP 2; AP2-alpha; activator protein 2; AP-

Entrez Gene ID

7020

UniProt ID

P05549

Product Background

Antigen Description

The AP2 proteins are normally expressed in ectodermally derived vertebrate tissues where they are necessary for normal growth and development. The factors have also been implicated in the control of cell proliferation, viral transformation, and oncogenesis. AP2 seems to play in important role in human breast cancer. AP2 alpha is the only AP2 protein required for early morphogenesis of the lens vesicle. AP2 beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia

Pathway

Caspase cascade in apoptosis, organism-specific biosystem; Wnt Signaling Pathway NetPath, organism-specific biosystem.

Citations