Anti-AMPH (full length) polyclonal antibody

Species Reactivity

Human

Immunogen

AMPH (AAH34376.1, 1 a.a. ~ 695 a.a) full-length recombinant protein with GST tag. The sequence is MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK PEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNG

Conjugate

Alternative Names

AMPH; amphiphysin; AMPH1; amphiphysin I; amphiphysin (Stiff-Mann syndrome with breast cancer 128kD autoantigen);

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. A pseudogene of this gene is found on chromosome 11.[provided by RefSeq, Nov 2010]

Pathway

Fc gamma R-mediated phagocytosis; Internalization of ErbB1;