Mouse anti-Human AKAP8 polyclonal antibody

Species Reactivity

Human

Immunogen

AKAP8 (NP_005849, 551 a.a. ~ 662 a.a) partial recombinant protein with GST tag. The sequence is VDPEMEGDDNLGGEDKKETPEEVAADVLAEVITAAVRAVDGEGAPAPESSGEPAEDEGPT DTAEAGSDPQAEQLLEEQVPCGTAHEKGVPKARSEAAEAGNGAETMAAEAES

Conjugate

Alternative Names

AKAP8; A kinase (PRKA) anchor protein 8; AKAP-8; AKAP95; AKAP 95; AKAP-95; A-kinase anchor protein 8; A-kinase anchor protein, 95kDa;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9.

Pathway

G Protein Signaling Pathways;