Anti-AGPAT1 monoclonal antibody (DCABH-10457) Made to order

Rabbit anti-Human AGPAT1 monoclonal antibody for WB, ELISA

View other AGPAT1 antibodies

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
A synthetic peptide of human AGPAT1 is used for rabbit immunization.
Conjugate
Unconjugated

Target


Alternative Names
AGPAT1; 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha); 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha; LPAAT alpha; 1-AGPAT 1; 1-AGP acyltransferase 1
Entrez Gene ID
UniProt ID

Product Background


Gene summary
AGPAT1 (1-Acylglycerol-3-Phosphate O-Acyltransferase 1) is a Protein Coding gene. Among its related pathways are Metabolism and Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha). GO annotations related to this gene include transferase activity, transferring acyl groups and 1-acylglycerol-3-phosphate O-acyltransferase activity. An important paralog of this gene is AGPAT2. This gene encodes an enzyme that converts lysophosphatidic acid (LPA) into phosphatidic acid (PA). LPA and PA are two phospholipids involved in signal transduction and in lipid biosynthesis in cells. This enzyme localizes to the endoplasmic reticulum. This gene is located in the class III region of the human major histocompatibility complex. Alternative splicing results in two transcript variants encoding the same protein.
Antigen Description
This gene encodes an enzyme that converts lysophosphatidic acid (LPA) into phosphatidic acid (PA). LPA and PA are two phospholipids involved in signal transduction and in lipid biosynthesis in cells. This enzyme localizes to the endoplasmic reticulum. This gene is located in the class III region of the human major histocompatibility complex. Alternative splicing results in two transcript variants encoding the same protein. Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha is an enzyme that in humans is encoded by the AGPAT1 gene. 0The function about AGPAT1 antigen include 1-acylglycerol-3-phosphate O-acyltransferase activity; transferase activity, transferring acyl groups.
Pathway
CDP-diacylglycerol biosynthesis I, organism-specific biosystem; CDP-diacylglycerol biosynthesis I, conserved biosystem; ChREBP activates metabolic gene expression, organism-specific biosystem; Fat digestion and absorption, organism-specific biosystem; Fat digestion and absorption, conserved biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Glycerolipid metabolism, organism-specific biosystem.

Citations


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We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Kumar, KG; Richards, BKS; et al. Transcriptional Profiling of Chromosome 17 Quantitative Trait Loci for Carbohydrate and Total Calorie Intake in a Mouse Congenic Strain Reveals Candidate Genes and Pathways. JOURNAL OF NUTRIGENETICS AND NUTRIGENOMICS 1:155-171(2008).
Boissonneault, G; Joly, M; et al. AGPAT1, a new histone acetyltransferase during spermatogenesis. BIOLOGY OF REPRODUCTION :300-301(2008).

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