Anti-ADSSL1 monoclonal antibody (DCABH-10447) Made to order

Rabbit anti-Human ADSSL1 monoclonal antibody for WB, ELISA

View other ADSSL1 antibodies

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
A synthetic peptide of human ADSSL1 is used for rabbit immunization.
Conjugate
Unconjugated

Target


Alternative Names
ADSSL1; adenylosuccinate synthase like 1; adenylosuccinate synthetase isozyme 1; FLJ38602; adSS 1; AMPSase 1
Entrez Gene ID
UniProt ID

Product Background


Gene summary
ADSSL1 (Adenylosuccinate Synthase Like 1) is a Protein Coding gene. Among its related pathways are Metabolism and Alanine, aspartate and glutamate metabolism. GO annotations related to this gene include protein homodimerization activity and GTPase activity. An important paralog of this gene is ADSS. This gene encodes a member of the adenylosuccinate synthase family of proteins. The encoded muscle-specific enzyme plays a role in the purine nucleotide cycle by catalyzing the first step in the conversion of inosine monophosphate (IMP) to adenosine monophosphate (AMP). Mutations in this gene may cause adolescent onset distal myopathy. Alternative splicing results in multiple transcript variants.
Antigen Description
ADSSL1 is a muscle isozyme of adenylosuccinate synthase (EC 6. 3. 4. 4), which catalyzes the initial reaction in the conversion of inosine monophosphate (IMP) to adenosine monophosphate (AMP) (Sun et al. , 2005 [PubMed 15786719]). Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). The function about ADSSL1 antigen include GTP binding; adenylosuccinate synthase activity; ligase activity; magnesium ion binding; nucleotide binding; phosphate ion binding.
Pathway
Alanine, aspartate and glutamate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of nucleotides, organism-specific biosystem; Purine metabolism, organism-specific biosystem; Purine metabolism, organism-specific biosystem.

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Donat, S; Streker, K; et al. Transcriptome and Functional Analysis of the Eukaryotic-Type Serine/Threonine Kinase PknB in Staphylococcus aureus. JOURNAL OF BACTERIOLOGY 191:4056-4069(2009).

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