Anti-ADH4 monoclonal antibody, clone FQS0593

Antibody Isotype

IgG

Clone

FQS0593

Species Reactivity

Human

Immunogen

Synthetic peptide (the amino acid sequence is considered to be commercially sensitive)

Conjugate

Application Notes

WB: 1/1000 - 1/10000.

Alternative Names

ADH4; alcohol dehydrogenase 4 (class II), pi polypeptide; alcohol dehydrogenase 4; ADH 2; aldehyde reductase; alcohol dehydrogenase class II pi chain; ADH-2;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes.

Pathway

Biological oxidations, organism-specific biosystem; Drug metabolism - cytochrome P450, organism-specific biosystem; Drug metabolism - cytochrome P450, conserved biosystem; Ethanol oxidation, organism-specific biosystem; Fatty Acid Omega Oxidation, organism-specific biosystem; Fatty acid metabolism, organism-specific biosystem; Fatty acid metabolism, conserved biosystem;