Anti-ADH1B monoclonal antibody, clone 5G23

Antibody Isotype

IgG2a

Clone

5G23

Species Reactivity

Rat; Dog; Human

Immunogen

Recombinant full length Human ADH1B (NP_000659) produced in HEK293T cells.

Conjugate

Application Notes

WB: 1/500; IHC-P: 1/150; Flow Cyt: 1/100; ICC/IF: 1/100;

Alternative Names

ADH1B; alcohol dehydrogenase 1B (class I), beta polypeptide; ADH2; alcohol dehydrogenase 1B; ADH, beta subunit; aldehyde reductase; alcohol dehydrogenase subunit beta; alcohol dehydrogenase 2 (class I), beta polypeptide;

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster.

Pathway

Biological oxidations, organism-specific biosystem; Drug metabolism - cytochrome P45, organism-specific biosystem; Drug metabolism - cytochrome P45, conserved biosystem; Ethanol oxidation, organism-specific biosystem; Fatty Acid Omega Oxidation, organism-specific biosystem; Fatty acid metabolism, organism-specific biosystem; Fatty acid metabolism, conserved biosystem.