Anti-ACPP (aa 247-259) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Synthetic peptide: C-YGIHKQKEKSRLQ, corresponding to internal sequence amino acids 247-259 of Human Prostatic Acid Phosphatase (NP_001090.2).

Conjugate

Application Notes

WB: 0.3 - 1 μg/ml; IHC-P: 3 - 5 μg/ml.

Alternative Names

ACPP; acid phosphatase, prostate; ACP3; 5-NT; ACP-3; prostatic acid phosphatase; TMPase; 5-nucleotidase; ecto-5-nucleotidase; thiamine monophosphatase; prostatic acid phosphotase;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway.

Pathway

Riboflavin metabolism;