Anti-5-Hydroxymethylcytidine monoclonal antibody (DMAB7951)

Mouse anti-5-Hydroxymethylcytidine monoclonal antibody for ELISA, Dot, IP Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
O298/60
Species Reactivity
N/A
Immunogen
Synthetic nucleoside of 5-hydroxymethylcytidine.
Conjugate
Unconjugated

Target


Alternative Names
5 hmC; 5 hme C; 5 hydroxy me C; 5 hydroxy me Cytidine; 5 hydroxy me Cytosine; 5 hydroxy methyl cytidine

Product Background


Antigen Description
5-Hydroxymethylcytosine is a DNA pyrimidine nitrogen base. It is formed from the DNA base cytosine by adding a methyl group and then a hydroxy group. It is important in epigenetics, because the hydroxymethyl group on the cytosine can possibly switch a gen.

Citations


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References


KOERNER, JF; VARADARAJAN, S; et al. PREPARATION OF DEOXY-5-HYDROXYMETHYLCYTIDINE TRIPHOSPHATE AND ITS MONOGLUCOSYL DERIVATIVE. JOURNAL OF BIOLOGICAL CHEMISTRY 235:2688-2690(1960).
Li, L; Xu, ZN; et al. The mildiomycin biosynthesis: Initial steps for sequential generation of 5-hydroxymethylcytidine 5 '-monophosphate and 5-hydroxymethylcytosine in Streptoverticillium rimofaciens ZJU5119. CHEMBIOCHEM 9:1286-1294(2008).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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