Adenovirus IgA ELISA Kit (DEIA310)

Regulatory status: For research use only, not for use in diagnostic procedures.

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Size
96T
Sample
serum, plasma
Species Reactivity
Human
Intended Use
The Adenovirus IgA Antibody ELISA Test Kit has been designed for the the detection and the quantitative determination of specific IgA antibodies against Adenovirus in serum and plasma.
Contents of Kit
1. Microtiter Strips
2. Calibrator A (Negative Control)
3. Calibrator B (Cut-Off Standard)
4. Calibrator C (Weak positive Control)
5. Calibrator D (Positive Control)
6. Enzyme Conjugate
7. Substrate
8. Stop Solution
9. Sample Diluent
10. Washing Buffer
11. Plastic Foils
Storage
For more detailed information, please download the following document on our website.
Sensitivity
1.00 U/mL

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References


Comment on "Cooperative Behaviors in Amplified Emission from Single Microcrystals of Thiophene/Phenylene Co-Oligomers toward Organic Polariton Laser"

ADVANCED OPTICAL MATERIALS

Authors: Paraschuk, Dmitry Yu.

Yanagi et al. recently reviewed their progress in the field of amplified emission of thiophene/phenylene co-oligomers (TPCO) single crystals (Adv. Opt. Mater. 2019, 7, 1900136), which are a promising platform for highly efficient organic light-emitting devices. In this comment, the most intriguing experimental data from this paper are naturally and easily explained as an effect of unintentional impurities or molecular self-dopants that appear in the course of chemical synthesis of TPCO.

Adenovirus Infections in African Humans and Wild Non-Human Primates: Great Diversity and Cross-Species Transmission

VIRUSES-BASEL

Authors: Medkour, Hacene; Amona, Inestin; Akiana, Jean; Davoust, Bernard; Bitam, Idir; Levasseur, Anthony; Tall, Mamadou Lamine; Diatta, Georges; Sokhna, Cheikh; Adriana Hernandez-Aguilar, Raquel; Barciela, Amanda; Gorsane, Slim; La Scola, Bernard; Raoult, Didier; Fenollar, Florence; Mediannikov, Oleg

Non-human primates (NHPs) are known hosts for adenoviruses (AdVs), so there is the possibility of the zoonotic or cross-species transmission of AdVs. As with humans, AdV infections in animals can cause diseases that range from asymptomatic to fatal. The aim of this study was to investigate the occurrence and diversity of AdVs in: (i) fecal samples of apes and monkeys from different African countries (Republic of Congo, Senegal, Djibouti and Algeria), (ii) stool of humans living near gorillas in the Republic of Congo, in order to explore the potential zoonotic risks. Samples were screened by real-time and standard PCRs, followed by the sequencing of the partial DNA polymerase gene in order to identify the AdV species. The prevalence was 3.3 folds higher in NHPs than in humans. More than 1/3 (35.8%) of the NHPs and 1/10 (10.5%) of the humans excreted AdVs in their feces. The positive rate was high in great apes (46%), with a maximum of 54.2% in chimpanzees (Pan troglodytes) and 35.9% in gorillas (Gorilla gorilla), followed by monkeys (25.6%), with 27.5% in Barbary macaques (Macaca sylvanus) and 23.1% in baboons (sevenPapio papioand sixPapio hamadryas). No green monkeys (Chlorocebus sabaeus) were found to be positive for AdVs. The AdVs detected in NHPs were members ofHuman mastadenovirus E(HAdV-E), HAdV-C or HAdV-B, and those in the humans belonged to HAdV-C or HAdV-D. HAdV-C members were detected in both gorillas and humans, with evidence of zoonotic transmission since phylogenetic analysis revealed that gorilla AdVs belonging to HAdV-C were genetically identical to strains detected in humans who had been living around gorillas, and, inversely, a HAdV-C member HAdV type was detected in gorillas. This confirms the gorilla-to-human transmission of adenovirus. which has been reported previously. In addition, HAdV-E members, the most often detected here, are widely distributed among NHP species regardless of their origin, i.e., HAdV-E members seem to lack host specificity. Virus isolation was successful from a human sample and the strain of the Mbo024 genome, of 35 kb, that was identified as belonging to HAdV-D, exhibited close identity to HAdV-D members for all genes. This study provides information on the AdVs that infect African NHPs and the human populations living nearby, with an evident zoonotic transmission. It is likely that AdVs crossed the species barrier between different NHP species (especially HAdV-E members), between NHPs and humans (especially HAdV-C), but also between humans, NHPs and other animal species.

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