Product Overview
Active Streptolysin O (Hemolytic streptococcus) full length protein
Tag/Conjugate
Unconjugated
Purity
> 95 % by SDS-PAGE.Purity >98% SDS-PAGE.
Buffer
Preservative: None Constituents: 50% Glycerol, PBS, 1mM DTT
Storage
Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles. Preservative: None Constituents: 50% Glycerol, PBS, 1mM DTT This product is an active protein and may elicit a biological response in vivo, handle with caution.
Introduction
Streptococcus pyogenes is a spherical, Gram-positive bacterium that is the cause of group A streptococcal infections. S. pyogenes displays streptococcal group A antigen on its cell wall. S. pyogenes typically produces large zones of beta-hemolysis (the co
Antigen Description
Streptolysin O (SLO) is a membrane-damaging extracellular toxin produced by hemolytic streptococci. The membrane-damaging activity is measured by hemolysis of red-blood cell. SLO is oxygen-sensitive and is easily inactivated in its presence but can be reactivated by thiol compounds , so it is also called thiol-activated cytolysin. SLO is produced not only by Group A hemolytic streptococci but also by Group C and Group G strains. The amino acid sequences are highly conserved among them and their homology is over 98%.
Keywords
Streptolysin O; Streptolysin O (Thiol-activated cytolysin) slo; S. pyogenes SLO; Streptococcus pyogenes SLO
Datasheet