HIV type 1 Active Glycoprotein 41 (subtype O ) (DAG-P2794)
HIV type 1 Active Glycoprotein 41 (full length) (subtype O ), recombinant protein from E. coli
Datasheet
Product Overview
Active HIV1 type O gp41 full length protein
Nature
Recombinant
Tag/Conjugate
Unconjugated
Cellular Localization
Viral envelope
Bio-activity
Active HIV1 type O gp41 full length protein is immunoreactive with all sera of HIV type O infected individuals
Purity
> 95 % by SDS-PAGE.
Format
Liquid
Buffer
Preservative: 0.02% Sodium Azide Constituents: 20mM Sodium carbonate, pH 9.6
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. Preservative: 0.02% Sodium Azide Constituents: 20mM Sodium carbonate, pH 9.6 This product is an active protein and may elicit a biological response in vivo, handle with
Introduction
The human immunodeficiency virus (HIV) is a lentivirus (slowly replicating retrovirus) that causes the acquired immunodeficiency syndrome (AIDS), a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic
Antigen Description
gp41 is a glycoprotein non-covalently-bound to gp120, and provides the second step by which HIV enters the cell. It is originally buried within the viral envelope, but, when gp120 binds to a CD4 receptor, gp120 changes its conformation, in such a way that the gp41 helps to initiate the process of membrane fusion between virus and cell.
Keywords
AIDS associated retrovirus; ARV; Env; glycoprotein 41; HIV-1 gp41; HIV1 gp41; HTLV III; Human immunodeficiency virus type 1 gp41; Human T lymphotropic virus III; LAV; Lymphadenopathy associated virus; HIV1 type O gp41
Citations
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