HIV type 1 Active Glycoprotein 120 (DAG-P2850)

HIV type 1 Active Glycoprotein 120 (aa 30 - 110), recombinant protein from E. coli Datasheet

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Product Overview
Active HIV1 gp120 protein fragment
Nature
Recombinant
Tag/Conjugate
Unconjugated
Cellular Localization
Envelope surface glycoprotein.
Bio-activity
Active HIV1 gp120 protein fragment is immunoreactive with all sera of HIV1 infected individuals.
Purity
> 95 % by SDS-PAGE.Purity is greater than 95.0% as determined by RP-HPLC and SDS-PAGE.
Format
Liquid
Buffer
Preservative: None Constituents: 8M Urea, 100mM Sodium phosphate, 10mM Tris HCl, pH 4.5
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Introduction
The human immunodeficiency virus (HIV) is a lentivirus (slowly replicating retrovirus) that causes the acquired immunodeficiency syndrome (AIDS), a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic
Antigen Description
The gp120 glycoprotein is used for binding to CD4 receptor and CCR5 co-receptor of T helper 2 (Th2) cells, and is able to induce FcepsilonRI(+) hematopoietic cells to produce IL4, which inactivates the host adaptive immune response.
Keywords
Glycoprotein 120; gp120; SU; Surface protein; HIV1 gp120

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