HIV type 1 Active Glycoprotein 120 (DAG-P2819)

HIV type 1 Active Glycoprotein 120 (full length), recombinant protein from Baculovirus Datasheet

Online Inquiry Add to basket

Product Overview
Active HIV1 gp120 full length protein
Nature
Recombinant
Tag/Conjugate
Unconjugated
Cellular Localization
Envelope surface glycoprotein.
Bio-activity
Active HIV1 gp120 full length protein is immunoreactive with sera from HIV infected individuals. It is dual tropic meaning it binds to CCR5 and X4.
Purity
> 90 % by SDS-PAGE.Purity is greater than 90.0% as determined by HPLC analysis and SDS-PAGE. Purified under conditions that maintain the tetriatary structure of the molecule.
Format
Liquid
Buffer
Preservative: None Constituents: 30mM Tris, 150mM Sodium chloride, 0.01% Tergitol, pH 7.6
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze/thaw cycles.
Introduction
The human immunodeficiency virus (HIV) is a lentivirus (slowly replicating retrovirus) that causes the acquired immunodeficiency syndrome (AIDS), a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic
Antigen Description
HIV1 is equipped with the envelope gp160 glycoprotein for interaction with Langerhans cells (LCs) and dendritic cells (DCs), the members of the innate immune system, which confront the virus at the portal of virus entry in the human body. These cells are equipped with receptors by which they bind and endocytose the virus. The gp120 glycoprotein is used for binding to CD4 receptor and CCR5 co-receptor of T helper 2 (Th2) cells, and is able to induce FcepsilonRI(+) hematopoietic cells to produce IL4, which inactivates the host adaptive immune response.
Keywords
Envelope surface glycoprotein gp120; Glycoprotein 120; gp120; gp120 glycoprotein; Human Immunodeficiency Virus 1; SU; Surface protein; HIV1 gp120

Citations


Have you cited DAG-P2819 in a publication? Let us know and earn a reward for your research.

Customer Reviews


Write a review, share your experiences with others and get rewarded !

Online Inquiry

Name
Phone *
E-mail Address *
Service & Products Interested *
Project Description
Verification Code * Please input "diagnostics" as verification code.

Online Inquiry

Order Info: HIV type 1 Active Glycoprotein 120

Online Inquiry
  Interested in larger quantities ? request a quote!
  Protocol may be improved. Please feel free to contact us to obtain the latest version.!
  15% off your first purchase

Ordering Information

Payment methods we support:
Invoice / Purchase Order
Credit card

OUR PROMISE TO YOU Guaranteed product quality expert customer support

Inquiry Basket