HIV Active Protease protein (DAG-P2124)

HIV Active Protease protein (aa 1 - 99), recombinant protein from E. coli Datasheet

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Product Overview
Active HIV protease protein fragment
Nature
Recombinant
Tag/Conjugate
Unconjugated
Molecular Weight
11 kDa
Bio-activity
Kinetic parameters: Km= 740 μM Kcat= 30 s-1 Kcat/Km= 4.1mM-1s-1 with peptide substrate ATLNFPISPW
Format
Liquid
Buffer
pH: 7.00Constituents: 0.24% Tris, 0.39% MES, 1.17% Sodium chloride, 10% Glycerol, 0.008% DTT, 0.05% Polyethylene glycol, 0.03% EDTA
Storage
Shipped on dry ice. Upon delivery aliquot and store at -80°C. Avoid freeze/thaw cycles.
Introduction
The human immunodeficiency virus (HIV) is a lentivirus (slowly replicating retrovirus) that causes the acquired immunodeficiency syndrome (AIDS), a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic
Antigen Description
A protease (also termed peptidase or proteinase) is any enzyme that performs proteolysis, that is, begins protein catabolism by hydrolysis of the peptide bonds that link amino acids together in the polypeptide chain forming the protein. Proteases have evolved multiple times, and different classes of protease can perform the same reaction by completely different catalytic mechanisms. Proteases can be found in animals, plants, bacteria, archea and viruses.
Keywords
HIV-1 protease; Human immunodeficiency virus protease; PR; Retropepsin; HIV protease

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