EBV Active Nuclear Antigen (DAG-P2818)

EBV Active Nuclear Antigen, recombinant protein from E. coli

Product Overview
Active EBV Nuclear Antigen protein fragment
Nature
Recombinant
Tag/Conjugate
Unconjugated
Cellular Localization
Nuclear. Free in the nucleoplasm, somewhat associated with the chromatin and hardly, if at all associated with the nuclear matrix.
Bio-activity
This protein is immunoreactive with sera of EBV-infected individuals
Procedure
None
Purity
> 95 % by SDS-PAGE.This protein was purified by proprietary chromatographic techniques.
Format
Liquid
Buffer
Preservative: None Constituents: 50% Glycerol, 0.5% Sarkosyl, 60mM Sodium chloride, 50mM Tris HCl, 10mM Glutathione
Preservative
None
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze/thaw cycles.
Introduction
The Epstein–Barr virus (EBV), also called human herpesvirus 4 (HHV-4), is a virus of the herpes family, and is one of the most common viruses in humans.

It is best known as the cause of infectious mononucleosis (glandular fever). It is also associated wi
Antigen Description
Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) is the one EBV antigen that is expressed in all EBV associated malignancies. It has long been thought to go undetected by the cell mediated immune system. However, recent studies show that EBNA1 can be presented to both CD4+ and CD8+ T cells, making it a potential new target for immunotherapy of EBV related cancers.
Keywords
EBNA1; EBV nuclear antigen 1; Epstein Barr nuclear antigen 1; Epstein Barr virus; HHV4; Human Herpesvirus 4; EBV Nuclear Antigen

Citations


Have you cited DAG-P2818 in a publication? Let us know and earn a reward for your research.

Customer Reviews


Write a review, share your experiences with others and get rewarded !
Product Name Cat. No. Applications Host Species Datasheet Price Add to Basket
Product Name Cat. No. Applications Host Species Datasheet Price Add to Basket

References


Paludan, C; Bickham, K; et al. Epstein-Barr nuclear antigen 1-specific CD4(+) Th1 cells kill Burkitt's lymphoma cells. JOURNAL OF IMMUNOLOGY 169:1593-1603(2002).
Lemons-Estes, FM; Capt, HP; et al. A clonal cutaneous CD30+lymphoproliferative eruption in a patient with evidence of past exposure to hepatitis E. INTERNATIONAL JOURNAL OF DERMATOLOGY 39:521-527(2000).

Online Inquiry

Name:
Phone: *
E-mail Address: *
Technology Interest:
Type of Organization:
Service & Products Interested: *
Project Description:
Verification code
Click image to refresh the verification code.

Online Inquiry

  Interested in larger quantities ? request a quote!
  Protocol may be improved. Please feel free to contact us to obtain the latest version.!

Ordering Information

Payment methods we support:
Invoice / Purchase Order
Credit card

OUR PROMISE TO YOU Guaranteed product quality expert customer support

Inquiry Basket