Molecular Weight
43.7 kDa
Purity
≥85% as determined by SDS-PAGE
Format
Liquid or Lyophilized powder
Buffer
Tris/PBS-based buffer, 5%-50% glycerol
Storage
Store at -20°C to -80°C
Introduction
Hepatitis B e-antigen (HBeAg) is a viral protein associated with HBV infections. Unlike the surface antigen, the e-antigen is found in the blood only when there are viruses also present. When the virus goes into "hiding," the e-antigen will no longer be present in the blood. HBeAg is often used as a marker of ability to spread the virus to other people (infectivity). Measurement of e-antigen may also be used to monitor the effectiveness of HBV treatment; successful treatment will usually eliminate HBeAg from the blood and lead to development of antibodies against eantigen (anti-HBe). There are some types (strains) of HBV that do not make e-antigen; these are especially common in the Middle East and Asia. In areas where these strains of HBV are common, testing for HBeAg is not very useful.
Keywords
Hepatitis B Virus E antigen; HBeAg; HBV; Hepatitis B Virus
Citations
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Wei, JN; Xue, SL; et al. Study of the relationship in pregnant women between hepatitis B markers and a placenta positive for hepatitis B surface antigen. JOURNAL OF PERINATAL MEDICINE 43:191-199(2015).
Jia, HY; Ding, F; et al. LAM add-on ADV combination therapy or ETV monotherapy for CHB patients with suboptimal response to ADV. ANNALS OF HEPATOLOGY 14:175-180(2015).
COA
Certificate of Analysis
