Human ACIN1 blocking peptide (CDBP0293)

Synthetic Human ACIN1 blocking peptide for BL

Product Overview
Acinus ( C - term ) peptide ( human )
Target
Acinus
Nature
Synthetic
Species Reactivity
Human
Tag/Conjugate
Unconjugated
Procedure
None
Concentration
0.2 mg/ml
Size
50 μg
Buffer
PBS with 0.1% BSA 0.02% sodium azide pH7.2
Preservative
0.02% Sodium Azide
Storage
Upon Receipt - Keep as concentrated solution. Aliquot and store at -20℃ or below. Avoid freeze-thaw cycles.
UniProt ID
Antigen Description
Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
Function
ATPase activity; enzyme binding; nucleic acid binding; nucleotide binding; poly(A) RNA binding; protein binding;
Synonyms
ACIN1; apoptotic chromatin condensation inducer 1; ACN; ACINUS; fSAP152; apoptotic chromatin condensation inducer in the nucleus; functional spliceosome-associated protein 152;

Citations


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References


Lund, PK; Namork, E; et al. The fate of monocytes during 24 h of culture as revealed by flow cytometry and electron microscopy. JOURNAL OF IMMUNOLOGICAL METHODS 270:63-76(2002).
Yan, Q; Sage, EH; et al. Transforming growth factor-beta 1 induces apoptotic cell death in cultured retinal endothelial cells but not pericytes: Association with decreased expression of p2l(waf1/cip1). JOURNAL OF CELLULAR BIOCHEMISTRY 70:70-83(1998).

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