The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2010]
Function
identical protein binding; protein binding
Synonyms
ATG16L1; autophagy related 16-like 1 (S. cerevisiae); IBD10; WDR30; APG16L; ATG16A; ATG16L; autophagy-related protein 16-1; APG16L beta; WD repeat domain 30; ATG16 autophagy related 16-like 1
Citations
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