Product Overview
Blocking peptide for anti-APOBEC3G antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not suitable for human or animal consumption.
Buffer
PBS containing 0.02% sodium azide
Preservative
0.02% Sodium Azide
Storage
Store at -20℃, stable for one year.
Antigen Description
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. The protein encoded by this gene has been found to be a specific inhibitor of human immunodeficiency virus-1 (HIV-1) infectivity.
Function
RNA binding; cytidine deaminase activity; hydrolase activity; metal ion binding; protein homodimerization activity; zinc ion binding;
Synonyms
APOBEC3G; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G; DNA dC->dU-editing enzyme APOBEC-3G; bK150C2.7; CEM15; dJ494G10.1; FLJ12740; MDS019; DNA dC-> dU-editing enzyme APOBEC-3G; APOBEC-related protein 9; dU editing enzyme; phorbolin-like protein MDS019; APOBEC-related cytidine deaminase; apolipoprotein B mRNA editing enzyme cytidine deaminase; ARCD; ARP9; ARP-9; CEM-15;
Citations
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Carr, JM; Coolen, C; et al. Human immunodeficiency virus 1 (HIV-1) virion infectivity factor (Vif) is part of reverse transcription complexes and acts as an accessory factor for reverse transcription. VIROLOGY 372:147-156(2008).
Smith, DS; Guo, KJ; et al. Noninfectious Retrovirus Particles Drive the Apobec3/Rfv3 Dependent Neutralizing Antibody Response. PLOS PATHOGENS 7:-(2011).