Product Overview
Blocking/Immunizing peptide for anti-APOBEC2 (aa180 - 190) antibody
Target
APOBEC2 (aa180 - 190)
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
APOBEC2 (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2) is a protein-coding gene. Diseases associated with APOBEC2 include tonsillitis, and thyroiditis. GO annotations related to this gene include cytidine deaminase activity and RNA binding. An important paralog of this gene is APOBEC3G.
Function
RNA binding; cytidine deaminase activity; hydrolase activity; metal ion binding; zinc ion binding;
Synonyms
APOBEC2; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2; probable C->U-editing enzyme APOBEC-2; ARCD1; ARP1; probable C-> U-editing enzyme APOBEC-2; apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2;
Citations
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Lada, AG; Iyer, LM; et al. Incarnation of classical pro- and eukaryotic mechanisms of mutagenesis in hypermutagenesis and immunity of vertebrates. RUSSIAN JOURNAL OF GENETICS 43:1093-1107(2007).
Santa-Marta, M; da Silva, FA; et al. HIV-1 Vif protein blocks the cytidine deaminase activity of B-cell specific AID in E-coli by a similar mechanism of action. MOLECULAR IMMUNOLOGY 44:583-590(2007).