Anti-ALPPL2 monoclonal antibody (DMABT-H13035)

Mouse anti-Human ALPPL2 monoclonal antibody for WB, IHC, IP, ELISA, RNAi Knockdown Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
3C4
Species Reactivity
Human
Immunogen
ALPPL2 (NP_112603, 365 a.a. ~ 454 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Target


Alternative Names
ALPPL2; alkaline phosphatase, placental-like 2; alkaline phosphatase, placental-like; ALP-1; Nagao isozyme; germ cell alkaline phosphatase
Entrez Gene ID
UniProt ID

Product Background


Gene summary
ALPPL2 (Alkaline Phosphatase, Placental Like 2) is a Protein Coding gene. Diseases associated with ALPPL2 include seminoma and gonadoblastoma. Among its related pathways are Metabolism and NAD metabolism. GO annotations related to this gene include phosphatase activity and alkaline phosphatase activity. An important paralog of this gene is ALPL. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The product of this gene is a membrane bound glycosylated enzyme, localized to testis, thymus and certain germ cell tumors, that is closely related to both the placental and intestinal forms of alkaline phosphatase.
Antigen Description
Protein Symbol:P10696-PPBN_HUMANRecommended name:Alkaline phosphatase, placental-likeProtein Accession:P10696Secondary Accessions:A8KAF2Q16727Q53S81Q96CM1The function about ALPPL2 antigen include alkaline phosphatase activity; hydrolase activity; metal ion binding.
Pathway
Folate biosynthesis, organism-specific biosystem; Folate biosynthesis, conserved biosystem; Metabolic pathways, organism-specific biosystem.

Citations


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References


Wennberg, C; Kozlenkov, A; et al. Structure, genomic DNA typing, and kinetic characterization of the D allozyme of placental alkaline phosphatase (PLAP/ALPP). HUMAN MUTATION 19:258-267(2002).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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