This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, May 2011]
Function
double-stranded DNA binding; poly(A) RNA binding; protein kinase A regulatory subunit binding; zinc ion binding;
Synonyms
AKAP8; A kinase (PRKA) anchor protein 8; AKAP-8; AKAP95; AKAP 95; AKAP-95; A-kinase anchor protein 8; A-kinase anchor protein, 95kDa;
Citations
Publication ()
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