Anti-ADPRH monoclonal antibody (DMABT-H12996)
Mouse anti-Human ADPRH monoclonal antibody for WB, IHC, sELISA, ELISA
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ADPRH (NP_001116.1, 23 a.a. ~232a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
ADPRH; ADP-ribosylarginine hydrolase; [Protein ADP-ribosylarginine] hydrolase; ARH1; ADP-ribose-L-arginine cleaving enzyme
ADPRH (ADP-Ribosylarginine Hydrolase) is a Protein Coding gene. Diseases associated with ADPRH include glycine n-methyltransferase deficiency and mucolipidosis ii alpha/beta. GO annotations related to this gene include magnesium ion binding and ADP-ribosylarginine hydrolase activity. An important paralog of this gene is ADPRHL1. The enzyme encoded by this gene catalyzes removal of mono-ADP-ribose from arginine residues of proteins in the ADP-ribosylation cycle. Unlike the rat and mouse enzymes that require DTT for maximal activity, the human enzyme is DTT-independent. Alternatively spliced transcript variants that encode different protein isoforms have been described.
Catalyzes the reverse reaction of mono-ADP-ribosylation. The function about ADPRH antigen include ADP-ribosylarginine hydrolase activity; hydrolase activity; magnesium ion binding.
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TAKADA, T; OKAZAKI, IJ; et al. ADP-RIBOSYLARGININE HYDROLASES. MOLECULAR AND CELLULAR BIOCHEMISTRY 138:119-122(1994).
Zolkiewska, A; Moss, J; et al. The alpha 7 integrin as a target protein for cell surface mono-ADP-ribosylation in muscle cells. ADP-RIBOSYLATION IN ANIMAL TISSUES: STRUCTURE, FUNCTION, AND BIOLOGY OF MONO (ADP-RIBOSYL) TRANSFERASES AND RELATED ENZYMES 419:297-303(1997).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.