Anti-ADAM17 monoclonal antibody (DMABT-H12989)
Mouse anti-Human ADAM17 monoclonal antibody for WB, IHC, sELISA, ELISA
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ADAM17 (NP_003174, 215 a.a. ~ 314 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
ADAM17; ADAM metallopeptidase domain 17; TACE, tumor necrosis factor, alpha, converting enzyme; disintegrin and metalloproteinase domain-containing protein 17; CD156B; cSVP
Activated NOTCH1 Transmits Signal to the Nucleus, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; Disease, organism-specific biosystem; Epithelial cell signaling in Helicobacter pylori infection, organism-specific biosystem;
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Haxaire, C; Blobel, CP; et al. With blood in the joint - what happens next? Could activation of a pro-inflammatory signalling axis leading to iRhom2/TNF alpha-convertase-dependent release of TNF alpha contribute to haemophilic arthropathy?. HAEMOPHILIA 20:11-14(2014).
Caiazza, F; Murphy, G; et al. ADAM17 as a Therapeutic Target for the Treatment of Breast Cancer: Preclinical Studies with an Inhibitory Monoclonal Antibody. EUROPEAN JOURNAL OF CANCER 48:162-163(2012).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.