Human ABCE1 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-ABCE1/ RNAse L inhibitor antibody

Target

ABCE1/ RNAse L inhibitor

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Function

ATP binding; ATPase activity; iron-sulfur cluster binding; ribonuclease inhibitor activity;

Synonyms

ABCE1; ATP-binding cassette, sub-family E (OABP), member 1; RLI; OABP; ABC38; RNS4I; RNASEL1; RNASELI; ATP-binding cassette sub-family E member 1; huHP68; RNase L inhibitor; ribonuclease 4 inhibitor; 2-5-oligoadenylate-binding protein; ribonuclease L (2,5-oligoisoadenylate synthetase-dependent) inhibitor;