Human AATF blocking peptide (CDBP0253)

Synthetic Human AATF blocking peptide for BL

Product Overview
Blocking peptide for anti-AATF antibody
Target
AATF
Nature
Synthetic
Species Reactivity
Human
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not suitable for human or animal consumption.
Procedure
None
Format
Liquid
Concentration
200 μg/ml
Size
50 μg
Buffer
PBS containing 0.02% sodium azide
Preservative
0.02% Sodium Azide
Storage
Store at -20℃, stable for one year.
UniProt ID
Antigen Description
The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis.
Function
leucine zipper domain binding; protein binding; protein domain specific binding; sequence-specific DNA binding transcription factor activity; tau protein binding;
Synonyms
AATF; apoptosis antagonizing transcription factor; protein AATF; CHE 1; CHE1; DED; rb-binding protein Che-1; apoptosis-antagonizing transcription factor; CHE-1;

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References


Sato, T; Selleri, C; et al. Expression and modulation of cellular receptors for interferon-gamma, tumour necrosis factor, and Fas on human bone marrow CD34(+) cells. BRITISH JOURNAL OF HAEMATOLOGY 97:356-365(1997).
Sjoblom, C; Wikland, M; et al. Granulocyte-macrophage colony-stimulating factor (GM-CSF) acts independently of the beta common subunit of the GM-CSF receptor to prevent inner cell mass apoptosis in human embryos. BIOLOGY OF REPRODUCTION 67:1817-1823(2002).

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