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Human SNAP23 ELISA Matched Antibody Pair   (ABPR-0874)  


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Species Reactivity
Human
Intended Use
This antibody pair set comes with matched antibody pair to detect and quantify protein level of human SNAP23.
General Description
Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene.
Reconstitution And Storage
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
Reagents And Materials Provided
Antibody pair set content:
1. Capture antibody: Magic™ rabbit affinity purified polyclonal anti-SNAP23 (100 μg)
2. Detection antibody: mouse monoclonal anti-SNAP23, IgG1 Kappa (20 μg)
Note: Reagents are sufficient for at least 3-5 x 96 well plates using recommended protocols.
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Order Info:Human SNAP23 ELISA Matched Antibody Pair
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United States
Tel: 1-631-624-4882
Fax: 1-631-938-8221
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Tel: 44-207-097-1828
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