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Cortisol-3 [BSA]   (DAG2979)  


Cortisol-3-BSA, synthetic           Datasheet

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Product Overview
Cortisol, BSA-Conjugated
Nature
Synthetic
Tag/Conjugate
BSA
Concentration
2.3 mg/ml
Preservative
Supplied in 0.015 M phosphate, 0.15 M NaCl, pH 7.2, 0.1% NaN3
Storage
2-8°C short term, -20°C long term
Introduction
Cortisol is the most potent glucocorticoid produced by the human adrenal. It is synthesized from cholesterol and its production is stimulated by pituitary adrenocorticotropic hormone (ACTH) which is regulated by corticotropin releasing factor (CRF). ACTH and CRF secretions are inhibited by high cortisol levels in a negative feedback loop. In plasma a majority of cortisol is bound with high affinity to corticosteroid binding globulin (CBG or transcotin). Cortisol acts through specific intracellular receptors and affects numerous physiologic systems including immune function, glucose counter regulation, vascular tone, and bone metabolism.
Keywords
Cortisol

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