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Magic™ Anti-BRCA1 monoclonal antibody   (DMAB4923MH)  


Armenian Hamster anti-Mouse PDCD1 monoclonal antibody for FC           Datasheet

Specifications
Host Species
Mouse
Antibody Isotype
IgM
Clone
HLK-3
Species Reactivity
Human
Immunogen
Peptidecorresponding to amino acids 1839-1863 of the C-terminus of BRCA1.
Conjugate
Unconjugated
Target
Alternative Names
BRCA1; breastcancer 1, early onset; IRIS; PSCP; BRCAI; BRCC1; PNCA4; RNF53; BROVCA1;breast cancer type 1 susceptibility protein; RING finger protein 53;BRCA1/BRCA2-containing complex, subunit 1; breast and ovarian cancersususceptibility protein; OTTHUMP00
Entrez Gene ID
672
UniProt ID
P38398
Product Background
Pathway
ATF-2 transcriptionfactor network; ATM mediated phosphorylation of repair proteins; AndrogenReceptor Signaling Pathway; BRCA1-associated genome surveillance complex;Coregulation of Androgen receptor activity; Double-Strand Break Repair;Fanconi anemia pathway; Homologous recombination repair ofreplication-independent double-strand breaks
References
Zhang, YQ; Pilyugin, M; et al. Expression of oncogenic BARD1 isoforms affects colon cancer progression and correlates with clinical outcome. BRITISH JOURNAL OF CANCER 107:675-683(2012).
Jiang, W; Qiu, WL; et al. Ginkgo may prevent genetic-associated ovarian cancer risk: multiple biomarkers and anticancer pathways induced by ginkgolide B in BRCA1-mutant ovarian epithelial cells. EUROPEAN JOURNAL OF CANCER PREVENTION 20:508-517(2011).

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Tel: 1-631-624-4882
Fax: 1-631-938-8221
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Tel: 44-207-048-3343
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