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Magic™ Anti-BRCA1 monoclonal antibody   (DMAB4923MH)  


Armenian Hamster anti-Mouse PDCD1 monoclonal antibody for FC           Datasheet

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Specifications
Host Species
Mouse
Antibody Isotype
IgM
Clone
HLK-3
Species Reactivity
Human
Immunogen
Peptidecorresponding to amino acids 1839-1863 of the C-terminus of BRCA1.
Conjugate
Unconjugated
Target
Alternative Names
BRCA1; breastcancer 1, early onset; IRIS; PSCP; BRCAI; BRCC1; PNCA4; RNF53; BROVCA1;breast cancer type 1 susceptibility protein; RING finger protein 53;BRCA1/BRCA2-containing complex, subunit 1; breast and ovarian cancersususceptibility protein; OTTHUMP00
Entrez Gene ID
672
UniProt ID
P38398
Product Background
Pathway
ATF-2 transcriptionfactor network; ATM mediated phosphorylation of repair proteins; AndrogenReceptor Signaling Pathway; BRCA1-associated genome surveillance complex;Coregulation of Androgen receptor activity; Double-Strand Break Repair;Fanconi anemia pathway; Homologous recombination repair ofreplication-independent double-strand breaks
References
Chalabi, N; Maurizis, JC; et al. Quantification by affinity perfusion chromatography of phosphorylated BRCA1 and BRCA2 proteins from tumor cells after lycopene treatment. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 821:188-193(2005).
Troudi, W; Uhrhammer, N; et al. Immunolocalization of BRCA1 protein in tumor breast tissue: prescreening of BRCA1 mutation in Tunisian patients with hereditary breast cancer?. EUROPEAN JOURNAL OF HISTOCHEMISTRY 51:219-226(2007).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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Protocol may be improved. Please feel free to contact us to obtain the latest version.
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Tel: 1-631-624-4882
Fax: 1-631-938-8221
Email:

Europe
Tel: 44-207-048-3343
Email:

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United States
Tel: 1-631-624-4882
Fax: 1-631-938-8221
Europe
Tel: 44-207-048-3343
Email

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