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Anti-Pneumolysin monoclonal antibody   (DMAB5766)  


Mouse anti-Streptococcus pneumoniae Pneumolysin monoclonal antibody for ELISA, WB           Datasheet

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Specifications
Host Species
Mouse
Antibody Isotype
IgG1
Clone
IZC 042-02
Species Reactivity
Streptococcus pneumoniae
Immunogen
Pneumolysin.
Conjugate
Unconjugated
Target
Alternative Names
Pneumolysin
Product Background
Antigen Description
Pneumolysin is a putative virulence factor of the gram-positive bacteria Streptococcus pneumoniae. Pneumolysin (pneumococcal hemolysin) is an intracellular protein produced by all strains of S. pneumoniae and is a cytoplasmic cholesterol-dependent cytolysin forming large pores in cholesterol-containing membranes and is therefore cytotoxic to mammalian cell. The molecular weight of pneumolysin is approximately 53 kD.
References
Mann, B; Thornton, J; et al. Broadly Protective Protein-Based Pneumococcal Vaccine Composed of Pneumolysin Toxoid-CbpA Peptide Recombinant Fusion Protein. JOURNAL OF INFECTIOUS DISEASES 209:1116-1125(2014).
Briles, DE; et al. Protection of the elderly from pneumococcal pneumonia with a protein-based vaccine?. MECHANISMS OF AGEING AND DEVELOPMENT 125:129-131(2004).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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Order Info:Anti-Pneumolysin monoclonal antibody
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Protocol may be improved. Please feel free to contact us to obtain the latest version.
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Tel: 1-631-624-4882
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United States
Tel: 1-631-624-4882
Fax: 1-631-938-8221
Europe
Tel: 44-207-048-3343
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