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Anti-MDV Monoclonal antibody   (DMAB3906)  


Mouse Anti-MDV Monoclonal antibody for ELISA, WB           Datasheet

Specifications
Host Species
Mouse
Antibody Isotype
IgG2a
Clone
C154M
Species Reactivity
MDV
Immunogen
MDV Strains SB-1 and Rispens
Conjugate
Unconjugated
Target
Alternative Names
Gallidherpesvirus 3; Gallidherpesvirus type 3; Marek"s disease herpesvirus 2; Marek"s disease virus type 2; MDV; Marek Disease Virus; Marek's Disease Virus; Herpesviridae; Mardivirus; Alphaherpesvirinae
Product Background
Antigen Description
Marek's Disease Virus, (MDV), is an oncogenic avian doublestranded DNA herpesvirus. It is highly contagious and results in aggressive T-cell lymphomas. Infection of MDV occurs via the respiratory tract, whereits uptake by macrophages and dendritic cells allows it to be transported inthe bloodstream to visceral organs and peripheral nerves, causing death in upto 80 percent of birds. It occurs in two main forms, depending on which partsof the body are affected by the tumours. In the nervous form the nerves,particulary the sciatic nerves, are affected. In the visceral form,greyish-white tumours are found in the ovaries, liver, spleen, kidney, heartand other organs. Suitable for use in ELISA and Western blot. Each laboratory should determine an optimum working titer foruse in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
References
OHASHI, K; OCONNELL, PH; et al. CHARACTERIZATION OF MAREKS-DISEASE VIRUS BAMHI-A-SPECIFIC CDNA CLONES OBTAINED FROM A MAREKS-DISEASE LYMPHOBLASTOID CELL-LINE. VIROLOGY 199:275-283(1994).
PENG, Q; ZENG, M; et al. ISOLATION AND CHARACTERIZATION OF MAREKS-DISEASE VIRUS (MDV) CDNAS MAPPING TO THE BAMHI-I-2, BAMHI-Q(2), AND BAMHI-L FRAGMENTS OF THE MDV GENOME FROM LYMPHOBLASTOID-CELLS TRANSFORMED AND PERSISTENTLY INFECTED WITH MDV. VIROLOGY 213:590-599(1995).

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United States
Tel: 1-631-624-4882
Fax: 1-631-938-8221
Europe
Tel: 44-207-048-3343
Email

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