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Anti-IL-2R monoclonal antibody   (DMAB3843MH)  


Mouse anti-Human IL-2R monoclonal antibody for FC           Datasheet

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Specifications
Host Species
Mouse
Antibody Isotype
IgG1
Clone
OR-73
Species Reactivity
Human
Immunogen
Con-A activated human PBL T cells.
Conjugate
Unconjugated
Target
Alternative Names
CD25; CD25 antigen; IDDM10; IL 2 RA; IL 2 receptor alpha subunit; IL 2R; IL2RAC a; Interleukin 2 receptor; Ly43; p55; T Cell Growth Factor Receptor; TAC Antigen; TCGFR; OTTHUMP00000019030; OTTHUMP00000019031; OTTHUMP00000019032
Entrez Gene ID
3559
UniProt ID
P01589
Product Background
Antigen Description
The function about IL-2R antigen include drug binding; interleukin-2 receptor activity; receptor activity.
Pathway
Arf6 trafficking events; Cytokine Signaling in Immune system; Downstream signaling in naive CD8+ T cells; IL12 signaling mediated by STAT4; Interleukin-3, 5 and GM-CSF signaling; Signaling by Interleukins.
References
Barclay, SL; Yang, YM; et al. Safety and Efficacy of a tCD25 Preselective Combination Anti-HIV Lentiviral Vector in Human Hematopoietic Stem and Progenitor Cells. STEM CELLS 33:870-879(2015).
Nelson, MH; Kundimi, S; et al. The Inducible Costimulator Augments Tc17 Cell Responses to Self and Tumor Tissue. JOURNAL OF IMMUNOLOGY 194:1737-1747(2015).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
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United States
Tel: 1-631-624-4882
Fax: 1-631-938-8221
Europe
Tel: 44-207-097-1828
Email

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