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Anti-UBE2W monoclonal antibody   (CABT-37525MH)  


Mouse anti-Human UBE2W monoclonal antibody for WB           Datasheet

Specifications
Host Species
Mouse
Antibody Isotype
IgG2a
Clone
EML338
Species Reactivity
Human
Immunogen
Recombinant fragment: KRLQKELLAL QNDPPPGMTL NEKSVQNSIT QWIVDMEGAP GTLYEGEKFQ LLFKFSSRYP FDSPQVMFTG ENIPVHPHVY SNGHICLSIL TEDWSP, corresponding to amino acids 17-113 of Human UBE2W
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 - 5μg/ml;

*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target
Alternative Names
UBE2W; ubiquitin-conjugating enzyme E2W (putative); probable ubiquitin-conjugating enzyme E2 W; FLJ11011; hUBC 16; hUBC16; Probable ubiquitin conjugating enzyme E2 W; Probable ubiquitin-conjugating enzyme E2 W; UBE 2W; ube2w; UBE2W_HUMAN; Ubiquitin carrie
Entrez Gene ID
55284
UniProt ID
Q96B02
Product Background
Pathway
Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem; Ubiquitin mediated proteolysis, organism-specific biosystem; Ubiquitin mediated proteolysis, conserved biosystem;
References
Christensen, DE; Brzovic, PS; et al. E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages. NATURE STRUCTURAL & MOLECULAR BIOLOGY 14:941-948(2007).
Tatham, MH; Plechanovova, A; et al. Ube2W conjugates ubiquitin to alpha-amino groups of protein N-termini. BIOCHEMICAL JOURNAL 453:137-145(2013).
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