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Anti-SOD1 monoclonal antibody   (CABT-37098RH)  


Rabbit anti-Human SOD1 monoclonal antibody for ICC/IF, IHC-P, IP, WB           Datasheet

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Specifications
Host Species
Rabbit
Antibody Isotype
IgG
Clone
FQS2837
Species Reactivity
Human
Immunogen
A synthetic peptide corresponding to residues in human Superoxide Dismutase 1
Conjugate
Unconjugated
Applications
Application Notes
ICC/IF 1/200; WB 1/100000 - 1/200000; IP 1/10; IHC-P: 1/250 - 1/500; ICC 1/100 - 1/250.

*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target
Alternative Names
SOD1; superoxide dismutase 1, soluble; ALS, ALS1,amyotrophic lateral sclerosis 1 (adult); superoxide dismutase [Cu-Zn]; IPOA; ALS; ALS1; Amyotrophic lateral sclerosis 1 adult; Cu/Zn SOD; Cu/Zn superoxide dismutase; Homodimer; hSod1; Indophenoloxidase A; I
Entrez Gene ID
6647
UniProt ID
P00441
Product Background
Pathway
Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; FOXA1 transcription factor network, organism-specific biosystem; Folate Metabolism, organism-specific biosystem; Hemostasis, organism-specific biosystem; Huntingtons disease, organism-specific biosystem; Huntingtons disease, conserved biosystem; Oxidative Stress, organism-specific biosystem; Peroxisome, organism-specific biosystem; Peroxisome, conserved biosystem; Platelet
References
Brown, HH; Borchelt, DR; et al. Analysis of Mutant SOD1 Electrophoretic Mobility by Blue Native Gel Electrophoresis; Evidence for Soluble Multimeric Assemblies. PLOS ONE 9:-(2014).
Redler, RL; Fee, L; et al. Non-native Soluble Oligomers of Cu/Zn Superoxide Dismutase (SOD1) Contain a Conformational Epitope Linked to Cytotoxicity in Amyotrophic Lateral Sclerosis (ALS). BIOCHEMISTRY 53:2423-2432(2014).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
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Tel: 1-631-624-4882
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United States
Tel: 1-631-624-4882
Fax: 1-631-938-8221
Europe
Tel: 44-207-097-1828
Email

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