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Anti-SNCA monoclonal antibody   (CABT-26489MH)  


Mouse anti-Human SNCA monoclonal antibody for IHC-P, WB           Datasheet

Specifications
Host Species
Mouse
Antibody Isotype
IgG
Clone
Tzo625
Species Reactivity
Human
Immunogen
Full length protein (Human): oxidized alpha synuclein.
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/500;

*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target
Alternative Names
SNCA; synuclein, alpha (non A4 component of amyloid precursor); PARK1, PARK4,Parkinson disease (autosomal dominant, Lewy body) 4; alpha-synuclein; alpha synuclein; NACP; PD1; Alpha synuclein; Alpha-synuclein; Alpha-synuclein, isoform NACP140; alphaSYN; MG
Entrez Gene ID
6622
UniProt ID
P37840
Product Background
Pathway
Alpha-synuclein signaling, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Amyloids, organism-specific biosystem; EGFR1 Signaling Pathway, organism-specific biosystem; Parkinsons disease, organism-specific biosystem;
References
Huang, L; Su, XM; et al. Single-Chain Fragment Variable Passive Immunotherapies for Neurodegenerative Diseases. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 14:19109-19127(2013).
Teng, YC; Jeng, CJ; et al. Role of autophagy in arsenite-induced neurotoxicity: The involvement of alpha-synuclein. TOXICOLOGY LETTERS 233:239-245(2015).

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